Which statement correctly differentiates an allergic reaction from anaphylaxis?

Which statement correctly differentiates an allergic reaction from anaphylaxis?

• A. Anaphylaxis is a mild skin reaction with itching.
• B. Allergic reactions always involve airway compromise.
• C. Allergic reactions are unrelated to anaphylaxis.
• D. Anaphylaxis is a severe systemic reaction with airway compromise, requiring prompt epinephrine; allergic reactions can range from mild to severe.

Answer: (D)